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International Joint Research Outcome - Prof. NAGASHIMA Hiroshi, School of Agriculture: Findings of his team indicated world's first that pig pluripotent stem cells (PSCs) allow for production of cloned individuals

Dec. 17, 2021

Professor NAGASHIMA Hiroshi (School of Agriculture; Director of Meiji University International Institute for Bio-Resource Research), Associate Professor MATSUNARI Hitomi (Organization for the Strategic Coordination of Research and Intellectual Properties), and UCHIKURA Ayuko (Researcher of Organization for the Strategic Coordination of Research and Intellectual Properties) worked as the team members of an international team of researchers, led by Professor Austin Smith from the University of Exeter’s Living Systems Institute. They have developed a new technique to obtain and multiply pluripotent embryonic stem cells from pig, sheep and cattle.

Findings of Meiji University team indicated world's first that pig pluripotent stem cells (PSCs) allow for production of cloned individuals. Meiji University team believes that pig PSCs have a great potential value as a resource in generating genetically engineered pigs for medical applications such as xenotransplantation and organ/tissue regeneration.

Reference
Title of original paper Pluripotent stem cells related to embryonic disc exhibit common self-renewal requirements in diverse livestock species
Journal Development
DOI 10.1242/dev.199901

Title of original paper The people behind the papers – Masaki Kinoshita, Toshihiro Kobayashi, Hiroshi Nagashima, Ramiro Alberio and Austin Smith
Journal Development
DOI 10.1242/dev.200347

▼Pioneering stem cell research could ease global sustainable food crisis (Professor Austin Smith, University of Exeter)
https://www.exeter.ac.uk/news/homepage/title_888861_en.html

▼Meiji University International Institute for Bio-Resource Research (MUIIBR)
https://www.meiji.ac.jp/cip/english/research/institute/muiibr.html

▼The Day Pigs Save Humans (Research Introduction Video of Prof. NAGASHIMA Hiroshi)