[Graduate School of Science and Technology] ZHU Xingyu wins the Best Poster Paper Award at Biomaterials International 2023
Oct. 03, 2023
ZHU Xingyu, a second-year Ph.D. student of the Applied Chemistry Program, Graduate School of Science and Technology (Laboratory of Biomaterials) won the Best Poster Paper Award at Biomaterials International 2023 (July 30 - August 3, held at Hokkaido University).
The Laboratory of Biomaterials (Professor AIZAWA Mamoru) is conducting research on antibacterial implants aimed at preventing post-surgical infections and related issues. In recent years, implant materials have become widely used in the field of oral surgery. However, issues such as peri-implantitis, which are associated with their usage, have arisen. Therefore, the Laboratory of Biomaterials is working to develop dental implants that combine resistance to infection with high soft tissue bonding properties.
In this study, antibacterial implants were fabricated using a method unique to the laboratory. First, titanium metal was coated with hydroxyapatite, known for its strong bone-binding properties. Then, silver ions, which possess antibacterial properties, were immobilized using the metal chelating ability of inositol phosphate. Furthermore, on top of that, basic fibroblast growth factor was loaded to create an oral surgical implant that prevents bacterial infections. Basic fibroblast growth factor is known to have the function of enhancing the bonding between implants and soft tissues. When investigating the antibacterial properties of the oral surgical implant prepared in this research, it was found that the implant exhibited antibacterial properties, inhibiting the growth of both Gram-positive and Gram-negative bacteria compared to samples without immobilized metal ions. It was also revealed that its antibacterial properties did not decrease even when loaded with basic fibroblast growth factor. These findings suggest that the antibacterial implants developed in this study have the potential to effectively protect against infections.
In recognition of the above research results, this study received the Best Poster Paper Award at Biomaterials International 2023 (out of 101 submissions, 15 were awarded). Biomaterials International 2023 brought together the international research community from various scientific fields, including biology, physiology, materials science, physics, chemistry, engineering, and clinical sciences, to discuss technologies and methodologies related to biomaterials.
This research was conducted in collaboration with the Department of Dentistry & Oral Surgery, Keio University School of Medicine, as one of the research subjects of Meiji University International Institute for Materials with Life Functions.
Award name: Best Poster Paper Award
Society name: Biomaterials International 2023
Presenter: 〇ZHU Xingyu, SUZUKI Kitaru, ONUMA Erika, ENJO Suzumi, MIYASHITA Hidetaka, SOMA Tomoya, NAKAGAWA Taneaki, MORIKAWA Satoru, AIZAWA Mamoru
Theme: Loading of basic fibroblast growth factor on apatite-coated titanium with anti-bacterial property and its material properties
≪Japanese version≫
The Laboratory of Biomaterials (Professor AIZAWA Mamoru) is conducting research on antibacterial implants aimed at preventing post-surgical infections and related issues. In recent years, implant materials have become widely used in the field of oral surgery. However, issues such as peri-implantitis, which are associated with their usage, have arisen. Therefore, the Laboratory of Biomaterials is working to develop dental implants that combine resistance to infection with high soft tissue bonding properties.
In this study, antibacterial implants were fabricated using a method unique to the laboratory. First, titanium metal was coated with hydroxyapatite, known for its strong bone-binding properties. Then, silver ions, which possess antibacterial properties, were immobilized using the metal chelating ability of inositol phosphate. Furthermore, on top of that, basic fibroblast growth factor was loaded to create an oral surgical implant that prevents bacterial infections. Basic fibroblast growth factor is known to have the function of enhancing the bonding between implants and soft tissues. When investigating the antibacterial properties of the oral surgical implant prepared in this research, it was found that the implant exhibited antibacterial properties, inhibiting the growth of both Gram-positive and Gram-negative bacteria compared to samples without immobilized metal ions. It was also revealed that its antibacterial properties did not decrease even when loaded with basic fibroblast growth factor. These findings suggest that the antibacterial implants developed in this study have the potential to effectively protect against infections.
In recognition of the above research results, this study received the Best Poster Paper Award at Biomaterials International 2023 (out of 101 submissions, 15 were awarded). Biomaterials International 2023 brought together the international research community from various scientific fields, including biology, physiology, materials science, physics, chemistry, engineering, and clinical sciences, to discuss technologies and methodologies related to biomaterials.
This research was conducted in collaboration with the Department of Dentistry & Oral Surgery, Keio University School of Medicine, as one of the research subjects of Meiji University International Institute for Materials with Life Functions.
Award name: Best Poster Paper Award
Society name: Biomaterials International 2023
Presenter: 〇ZHU Xingyu, SUZUKI Kitaru, ONUMA Erika, ENJO Suzumi, MIYASHITA Hidetaka, SOMA Tomoya, NAKAGAWA Taneaki, MORIKAWA Satoru, AIZAWA Mamoru
Theme: Loading of basic fibroblast growth factor on apatite-coated titanium with anti-bacterial property and its material properties
≪Japanese version≫
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