[Graduate School of Science and Technology] NOSE Masato wins the Young Scientist Presentation Award at the 32nd Inorganic Phosphorus Chemistry Symposium
Oct. 10, 2023
NOSE Masato, a student in the Applied Chemistry Program at Graduate School of Science and Technology (Laboratory of Biomaterial) won the Young Scientist Presentation Award at the 32nd Inorganic Phosphorus Chemistry Symposium (held from September 21 to 22).
The Laboratory of Biomaterials in the Applied Chemistry Program (Professor AIZAWA Mamoru) is actively engaged in research on “bio ceramics that actively work on the immune system,” useful for adoptive immunotherapy (cellular immunotherapy), which is gaining attention as a novel approach to cancer treatment. Adoptive immunotherapy is a treatment method involving the cultivation of a patient’s own immune cells outside the body, followed by reintroduction into the patient’s system to enhance their immune response, and is expected to be a new cancer treatment with the advantage of its low risk of side effects
The laboratory has investigated the activation of immune cells during the cell culture phase of adoptive immunotherapy, using CaO-P2O5-SiO2-B2O3 (CPSB)-based ceramics as a culture substrate. This presentation demonstrates that the administration of immune cells cultured on CPSB-based ceramics significantly inhibited tumor growth in mice that had cancer. Based on these findings, CPSB-based ceramics hold great potential as culture substrates for application in adoptive immunotherapy.
In recognition of the above research results, this study received the Young Scientist Presentation Award. The Japanese Association of Inorganic Phosphorus Chemistry was established based on the first Inorganic Phosphorus Chemistry Symposium (1973) and the subsequent meeting of inorganic phosphorus chemistry researchers. The aim of the association is to develop and utilize the science and technology related to inorganic substances containing phosphorus, as well as materials or phenomena associated with them. We conduct discussions and information exchanges, and this marks the 32nd edition of the event.
This research was conducted with support from KAKENHI (Challenging Research (Exploratory)) and in collaboration with the Meiji University International Institute for Materials with Life Functions. The research findings are the outcome of collaborative research between the University and the Department of Molecular Immunology, Graduate School, and Faculty of Medicine at Tokyo Medical and Dental University (Associate Professor NAGAI Shigenori).
Award name: Young Scientist Presentation Award
Society name: The 32nd Inorganic Phosphorus Chemistry Symposium
Presenter: 〇NOSE Masato, KIZUKURI Rihoko, NAGAO Yuki, NITTA Aiko, ZHENG YUNDI, FUKUDA Ryuichi, NAGAI Shigenori, AIZAWA Mamoru
Title: Preparation of CaO-P2O5-SiO2-B2O3-based ceramics for use in adoptive immunotherapy and the validation of their anti-tumor effects in mice with tumors
≪Japanese version≫
The Laboratory of Biomaterials in the Applied Chemistry Program (Professor AIZAWA Mamoru) is actively engaged in research on “bio ceramics that actively work on the immune system,” useful for adoptive immunotherapy (cellular immunotherapy), which is gaining attention as a novel approach to cancer treatment. Adoptive immunotherapy is a treatment method involving the cultivation of a patient’s own immune cells outside the body, followed by reintroduction into the patient’s system to enhance their immune response, and is expected to be a new cancer treatment with the advantage of its low risk of side effects
The laboratory has investigated the activation of immune cells during the cell culture phase of adoptive immunotherapy, using CaO-P2O5-SiO2-B2O3 (CPSB)-based ceramics as a culture substrate. This presentation demonstrates that the administration of immune cells cultured on CPSB-based ceramics significantly inhibited tumor growth in mice that had cancer. Based on these findings, CPSB-based ceramics hold great potential as culture substrates for application in adoptive immunotherapy.
In recognition of the above research results, this study received the Young Scientist Presentation Award. The Japanese Association of Inorganic Phosphorus Chemistry was established based on the first Inorganic Phosphorus Chemistry Symposium (1973) and the subsequent meeting of inorganic phosphorus chemistry researchers. The aim of the association is to develop and utilize the science and technology related to inorganic substances containing phosphorus, as well as materials or phenomena associated with them. We conduct discussions and information exchanges, and this marks the 32nd edition of the event.
This research was conducted with support from KAKENHI (Challenging Research (Exploratory)) and in collaboration with the Meiji University International Institute for Materials with Life Functions. The research findings are the outcome of collaborative research between the University and the Department of Molecular Immunology, Graduate School, and Faculty of Medicine at Tokyo Medical and Dental University (Associate Professor NAGAI Shigenori).
Award name: Young Scientist Presentation Award
Society name: The 32nd Inorganic Phosphorus Chemistry Symposium
Presenter: 〇NOSE Masato, KIZUKURI Rihoko, NAGAO Yuki, NITTA Aiko, ZHENG YUNDI, FUKUDA Ryuichi, NAGAI Shigenori, AIZAWA Mamoru
Title: Preparation of CaO-P2O5-SiO2-B2O3-based ceramics for use in adoptive immunotherapy and the validation of their anti-tumor effects in mice with tumors
≪Japanese version≫
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