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[Graduate School of Science and Technology] HORIKAWA Shota received the Society of Inorganic Materials Award for Excellent Lecture at the 147th Scientific Lecture Meeting of the Society of Inorganic Materials, Japan

Nov. 28, 2023

Mr. HORIKAWA Shota (Laboratory of Biomaterials), a second-year student in the Master’s program of the Applied Chemistry Program at the Graduate School of Science and Technology, received the Society of Inorganic Materials Award for Excellent Lecture at the 147th Scientific Lecture Meeting of the Society of Inorganic Materials, Japan held at the Katahira Campus of Tohoku University on November 9 and 10, 2023.

The Laboratory of Biomaterials (Professor AIZAWA Mamoru) is developing bioceramics such as hydroxy apatite (HAp) and beta-tricalcium phosphate (b-TCP), which are clinically applied as artificial bone materials. However, in order to develop artificial bone materials, it is necessary to conduct animal experiments to ensure safety in vivo, but the reduction of animal experiments is required from the viewpoint of animal welfare. In this research, the Laboratory aims to use machine learning for the development of artificial bone materials, construct a bone formation estimation model that can predict the safety and performance of newly created artificial bone materials, and establish an alternative animal experiment method to replace animal experiments.

In this presentation, Mr. HORIKAWA actually produced a material under experimental conditions calculated by inverse analysis of the bone formation estimation model, evaluated the material properties, and verified the reaction of living hard tissue implanted in a pig tibia. Mr. HORIKAWA succeeded in producing a material that matched the estimated values of the inverse analysis. These findings are expected to lead to the establishment of an alternative animal experimental method by constructing a new artificial bone material development process utilizing machine learning.

This research achievement was recognized, resulting in the receipt of the Society of Inorganic Materials Award for Excellent Lecture (7 out of 37 were awarded). The Society of Inorganic Materials, Japan is an academic society that strives to develop and study technologies for the promotion of academic science and industrial development related to inorganic materials and one of the traditional academic societies specializing in inorganic materials, having been founded over 70 years ago. This was the 147th lecture meeting held.

Also, this research was conducted in collaboration with the Data Chemical Engineering Laboratory of the Department of Applied Chemistry, Meiji University (Associate Professor KANEKO Hiromasa) and the International Institute for Bio-Resource Research, Meiji University (Representative: Professor NAGASHIMA Hiroshi, School of Agriculture), as part of Grant-in-Aid for Scientific Research (Basic Research B) and the Meiji University International Institute for Materials with Life Functions.

Award name: The Society of Inorganic Materials Award for Excellent Lecture
Society name: The 147th Scientific Lecture Meeting of the Society of Inorganic Materials, Japan .
Presenters: ○HORIKAWA Shota, SUZUKI Kitaru, MOTOJIMA Kohei, NAKANO Kazuaki, NAGAYA Masaki, NAGASHIMA Horoshi, KANEKO Hiromasa, AIZAWA Mamoru 
Subject: Verification of material properties of porous calcium phosphate ceramics designed by machine learning and their living hard tissue reaction

Japanese version≫