[Graduate School of Science and Technology] ZHONG Xinglin wins the Young Scientist Presentation Award at the 34th Inorganic Phosphorus Chemistry Symposium
Oct. 18, 2025
ZHONG Xinglin, a second-year student on the master’s course in the Applied Chemistry Program, the Graduate School of Science and Technology (AIZAWA Laboratory), received the Young Scientist Presentation Award at the 34th Inorganic Phosphorus Chemistry Symposium.
The Laboratory of Biomaterials (Professor AIZAWA Mamoru) in the Department of Applied Chemistry, the School of Science and Technology is working on nervous tissue regeneration by tissue engineering using hydroxyapatite (HAp), a major inorganic component in living bone. Tissue engineering is a technology that regenerates tissue by combining three elements: cells, growth factors, and scaffold materials.
This laboratory works on the development of apatite fiber scaffold (AFS), which has excellent biocompatibility as a scaffold material capable of three-dimensional culture and has communication pores through which cells can enter. The ultimate goal of this research is to construct nervous tissue with three-dimensional higher-order structure. In this research, ZHONG used apatite-fiber scaffold (AFS) and radial-flow bioreactor (RFB) to culture neural stem and progenitor cells derived from neonatal mouse brains in a three-dimensional dynamic environment, and evaluated their cell proliferation and histology. As a result, it became clear that by using RFB, cells could easily invade the interior of AFS, which is a three-dimensional culture substratum, and that regenerative tissue with relatively homogeneous cell distribution could be constructed while maintaining a good progenitor cell property.
This research achievement was recognized, resulting in the receipt of the Young Scientist Presentation Award. The Japanese Association of Inorganic Phosphorus Chemistry is a specialized association focused on phosphorus-containing inorganic substances and related substances. This event marks the 34th Inorganic Phosphorus Chemistry Symposium.
This research is one of the sub-themes of the Meiji University International Institute for Materials with Life Functions and was conducted in collaboration with the Department of Immunology and Medicine at St. Marianna University School of Medicine.
Award name: Young Scientist Presentation Award
Conference name: The 34th Inorganic Phosphorus Chemistry Symposium
Venue: Main Building Large Lecture Room, Graduate School of Environmental Studies, Aobayama Campus, Tohoku University
Dates: September 11-12, 2025 (Presentation date: September 11, 2025)
Presenter: ZHONG Xinglin, SUZUKI Kitaru, MIYABE Yoshishige, NAKATA (ARIMITSU) Nagisa, AIZAWA Mamoru
Title: Three-Dimensional Circular Type Culture of Mouse Neural Stem and Progenitor Cells Using Radial-Flow Bioreactor and Apatite-Fiber Scaffold