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[Graduate School of Science and Technology] HASHIMOTO Mizuki is honored with the Outstanding Presentation Encouragement Award and the JAICI Award for the presentation at the SIMJ lecture meeting

Jan. 30, 2025

The Laboratory of Biomaterials (Professor AIZAWA Mamoru) in the Applied Chemistry Program of Graduate School of Science and Technology has been promoting the development of bioceramics such as hydroxyapatite (HAp) and β-tricalcium phosphate (β-TCP), which are key inorganic components of human teeth and bones and have been clinically applied as artificial bone materials. Although artificial bone materials offer advantages such as shape flexibility and unlimited supply, they are inferior to autologous bone (the patient's own bone) in bone formation ability. The bioapatite in autologous bone contains various bone minerals, including Na⁺, K⁺, Mg²⁺, F⁻, and CO₃²⁻, and features numerous nanoscale defects within its crystal structure. These factors are considered to be one of the factors that contribute to superior bone formation ability. This study aims to fabricate materials in which HAp is co-substituted with Mg²⁺ and Zn²⁺ ions, which are trace elements in the body, and to elucidate the synergistic effects of these two cations.

In this presentation, materials with Mg²⁺ and Zn²⁺ ions co-substituted into hydroxyapatite (HAp) to form a solid solution were fabricated. The properties of the obtained materials were evaluated, and crystal structure analysis was successfully performed using Rietveld analysis via X-ray diffraction. These findings can be considered to lead to the control of the elution amount of Mg²⁺ and Zn²⁺ ions, which are expected to improve bone formation ability.

The above research results were recognized, leading to receipt of the Outstanding Presentation Award at the meeting of the Society of Inorganic Materials, Japan (7 recipients selected from 34 presentations). The Japan Society of Inorganic Materials (SIMJ) is an academic society that strives for technological development and study for the promotion of academics and industrial development related to inorganic materials, and is one of the long-established societies specializing in inorganic materials, set to celebrate its 75th anniversary in 2025. This is the 149th lecture meeting.

Award name: Outstanding Presentation Encouragement Award and the JAICI Award for the presentation at the SIMJ lecture meeting 
Society name: The Society of Inorganic Materials, Japan
Presenters: 〇HASHIMOTO Mizuki, AIKAWA Shoma, HIROSAWA Shunn, FUKASAWA Tomoko, AIZAWA Mamoru
Presentation Title: Crystal structure analysis of hydroxyapatite ceramics co-substituted with Mg2+ and Zn2+ ions prepared by ultrasonic spray pyrolysis  
 

Japanese version